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The Armitage–Doll model is a statistical model of carcinogenesis, proposed in 1954 by Peter Armitage and Richard Doll, which suggested that a sequence of multiple distinct genetic events preceded the onset of cancer. The original paper has recently been reprinted with a set of commentary articles. ==References== * Armitage, P. and Doll, R. (1954) ("The Age Distribution of Cancer and a Multi-Stage Theory Of Carcinogenesis" ), ''British Journ. of Cancer'', 8 (1), 1-12. Reprinted (2004): (reprint ), ''British Journal of Cancer'', 91, 1983–1989. *P Armitage and R Doll (2004) "The age distribution of cancer and a multi-stage theory of carcinogenosis", ''Int. J. Epidemiol'' 33(6): 1174-1179 *Steven A Frank (2004) "Commentary: Mathematical models of cancer progression and epidemiology in the age of high throughput genomics", ''Int. J. Epidemiol.'' 33(6): 1179-1181 *Suresh H Moolgavkar (2004) "Commentary: Fifty years of the multistage model: remarks on a landmark paper", ''Int. J. Epidemiol.'' 33(6): 1182-1183 *Richard Doll (2004) "Commentary: The age distribution of cancer and a multistage theory of carcinogenesis", ''Int. J. Epidemiol.'' 33(6): 1183-1184 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Armitage–Doll multistage model of carcinogenesis」の詳細全文を読む スポンサード リンク
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