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Armitage–Doll multistage model of carcinogenesis
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Armitage–Doll multistage model of carcinogenesis : ウィキペディア英語版
Armitage–Doll multistage model of carcinogenesis
The Armitage–Doll model is a statistical model of carcinogenesis, proposed in 1954 by Peter Armitage and Richard Doll, which suggested that a sequence of multiple distinct genetic events preceded the onset of cancer. The original paper has recently been reprinted with a set of commentary articles.
==References==

* Armitage, P. and Doll, R. (1954) ("The Age Distribution of Cancer and a Multi-Stage Theory Of Carcinogenesis" ), ''British Journ. of Cancer'', 8 (1), 1-12. Reprinted (2004): (reprint ), ''British Journal of Cancer'', 91, 1983–1989.
*P Armitage and R Doll (2004) "The age distribution of cancer and a multi-stage theory of carcinogenosis", ''Int. J. Epidemiol'' 33(6): 1174-1179
*Steven A Frank (2004) "Commentary: Mathematical models of cancer progression and epidemiology in the age of high throughput genomics", ''Int. J. Epidemiol.'' 33(6): 1179-1181
*Suresh H Moolgavkar (2004) "Commentary: Fifty years of the multistage model: remarks on a landmark paper", ''Int. J. Epidemiol.'' 33(6): 1182-1183
*Richard Doll (2004) "Commentary: The age distribution of cancer and a multistage theory of carcinogenesis", ''Int. J. Epidemiol.'' 33(6): 1183-1184


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